Laszlo Otvos Selected Research

Adiponectin Receptors

12/2020	Adiponectin receptor activation inhibits prostate cancer xenograft growth.
1/2017	Adiponectin is an endogenous anti-fibrotic mediator and therapeutic target.
5/2015	Molecular targeting of obesity pathways in cancer.
6/2014	Designer adiponectin receptor agonist stabilizes metabolic function and prevents brain injury caused by HIV protease inhibitors.
1/2014	Development of second generation peptides modulating cellular adiponectin receptor responses.
10/2011	Design and development of a peptide-based adiponectin receptor agonist for cancer treatment.

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Laszlo Otvos Research Topics

Disease

15	Neoplasms (Cancer) 01/2021 - 05/2002
13	Infections 01/2019 - 12/2002
7	Obesity 01/2021 - 07/2011
5	Wounds and Injuries (Trauma) 01/2016 - 11/2010
5	Breast Neoplasms (Breast Cancer) 01/2014 - 11/2004
4	Bacterial Infections (Bacterial Infection) 03/2022 - 10/2014
3	Inflammation (Inflammations) 01/2021 - 12/2013
3	Bacteremia 01/2018 - 01/2011
3	Cardiovascular Diseases (Cardiovascular Disease) 05/2016 - 10/2011
3	Wound Infection (Wound Infections) 07/2015 - 11/2010
2	Body Weight (Weight, Body) 01/2021 - 01/2011
2	Hypertension (High Blood Pressure) 01/2021 - 05/2016
2	Prostatic Neoplasms (Prostate Cancer) 01/2021 - 12/2020
2	Hypoadiponectinemia 12/2020 - 06/2014
2	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 04/2014 - 01/2014
2	Glioblastoma (Glioblastoma Multiforme) 01/2014 - 07/2011
2	Burns 12/2013 - 11/2010
2	Virus Diseases (Viral Diseases) 01/2008 - 06/2003
2	Human Influenza (Influenza) 07/2006 - 06/2003
2	Urinary Tract Infections (Urinary Tract Infection) 08/2005 - 06/2003
1	Hypoxia (Hypoxemia) 01/2021
1	Apnea 01/2021
1	Melioidosis 01/2018
1	Fibrosis (Cirrhosis) 01/2017
1	Systemic Scleroderma (Systemic Sclerosis) 01/2017
1	Peritoneal Fibrosis 01/2017
1	Hypersensitivity (Allergy) 05/2016
1	Diabetic Retinopathy (Retinopathy, Diabetic) 01/2016
1	Macular Degeneration (Age-Related Maculopathy) 01/2016
1	Macular Edema 01/2016
1	Choroidal Neovascularization 01/2016
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 06/2014
1	Neurocognitive Disorders (Clerambault Syndrome) 06/2014
1	Cognitive Dysfunction 06/2014
1	Hypertriglyceridemia 06/2014
1	Hyperinsulinism (Hyperinsulinemia) 06/2014
1	Brain Injuries (Brain Injury) 06/2014
1	Colorectal Neoplasms (Colorectal Cancer) 06/2013
1	Insulin Resistance 10/2011
1	Rheumatoid Arthritis 08/2011
1	Arthritis (Polyarthritis) 08/2011
1	Autoimmune Diseases (Autoimmune Disease) 08/2011
1	Brain Neoplasms (Brain Tumor) 07/2011
1	Triple Negative Breast Neoplasms 07/2011
1	Cross Infection (Nosocomial Infection) 05/2011
1	Foot Ulcer 05/2011
1	Weight Gain 01/2011
1	Cachexia 01/2011
1	Blast Injuries 11/2010
1	Escherichia coli Infections 04/2010

Drug/Important Bio-Agent (IBA)

25	Peptides (Polypeptides)IBA 12/2020 - 05/2002
12	LeptinIBA 01/2021 - 10/2008
9	Proline (L-Proline)FDA Link 03/2022 - 07/2008
8	Antimicrobial PeptidesIBA 03/2022 - 05/2011
7	Leptin ReceptorsIBA 01/2021 - 01/2011
6	AdipokinesIBA 01/2021 - 10/2011
6	AdiponectinIBA 12/2020 - 10/2011
6	Adiponectin ReceptorsIBA 12/2020 - 10/2011
6	Anti-Bacterial Agents (Antibiotics)IBA 01/2016 - 06/2003
5	Hormones (Hormone)IBA 01/2021 - 10/2008
4	asparaginyl- isoleucyl- prolyl- norvalyl- leucyl- tyrosyl- seryl- phenylalanyl- alanyl- serinamideIBA 12/2020 - 01/2014
4	Antimicrobial Cationic PeptidesIBA 01/2017 - 07/2015
3	Colistin (Coly-Mycin)FDA Link 01/2018 - 05/2011
3	Pharmaceutical PreparationsIBA 10/2014 - 01/2011
3	Proteins (Proteins, Gene)FDA Link 01/2008 - 06/2003
2	AmidesIBA 01/2019 - 01/2018
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2016 - 07/2011
2	Protein Subunit VaccinesIBA 01/2008 - 06/2003
1	AndrogensIBA 01/2021
1	Oxygen (Dioxygen)IBA 01/2021
1	Insulin (Novolin)FDA Link 12/2020
1	Ceftazidime (Fortum)FDA LinkGeneric 01/2018
1	Arginine (L-Arginine)FDA Link 01/2017
1	Adenosine Monophosphate (AMP)IBA 01/2017
1	CatecholaminesIBA 05/2016
1	Cytochrome P-450 CYP11B2 (CYP11B2)IBA 05/2016
1	AldosteroneIBA 05/2016
1	Non-Receptor Type 1 Protein Tyrosine PhosphataseIBA 05/2016
1	A 113IBA 05/2016
1	Polyvinyl AlcoholIBA 01/2016
1	PolymersIBA 01/2016
1	HIV Protease InhibitorsIBA 06/2014
1	Peptide Hydrolases (Proteases)FDA Link 04/2014
1	Bacterial Proteins (Bacterial Protein)IBA 04/2014
1	Biotin (Vitamin H)FDA Link 04/2014
1	Methicillin (Metin)FDA Link 12/2013
1	Amino Acids FDA Link 01/2013
1	Biological ProductsIBA 10/2011
1	Adenosine Diphosphate (ADP)IBA 10/2011
1	PeptidomimeticsIBA 10/2011
1	Imipenem FDA Link 05/2011
1	AerosolsIBA 05/2011
1	Amikacin (A.M.K)FDA LinkGeneric 05/2011
1	Carbapenems (Carbapenem Antibiotics)IBA 01/2011

Therapy/Procedure

7	Therapeutics 01/2021 - 10/2007
1	Drug Therapy (Chemotherapy) 01/2021
1	Lasers (Laser) 01/2016
1	Mechanical Ventilators (Ventilator) 05/2011
1	Aftercare (After-Treatment) 05/2011
1	Intranasal Administration 01/2011